Table 3.

EC₅₀ values for 16-wk-old rats

	KCl, mM	Carbachol, μM	Bethanechol, μM	ATP, mM
Cumulative
Control	36.4 ± 2.8	0.6 ± 0.2	16.0 ± 2.9	0.7 ± 0.2
Diabetic	27.2 ± 2.1*	0.7 ± 0.2	11.4 ± 2.4	1.3 ± 0.4
Noncumulative
Control	48.5 ± 2.4	0.4 ± 0.0	11.4 ± 1.7	1.1 ± 3.2
Diabetic	43.5 ± 1.6	0.4 ± 0.1	9.2 ± 0.9	0.7 ± 0.2

Values are means ± SE of 5–6 determinations, each from a different animal. Statistical comparisons were made between control and diabetic animals within the same treatment group using Student's t-test.

^*P < 0.05 compared with control animals.