Table 3.
Effect of AVP-induced hypertension on the autoregulatory response of renal vascular resistance to a RPP step
| RPP, mmHg |
RBF, ml·min−1·g KW−1 |
Slope, %/s |
Termination Point, s |
|||||
|---|---|---|---|---|---|---|---|---|
| Prestep | Poststep | Prestep | Poststep | Stage 1 | Stage 2 | Stage 1 | Stage 2 | |
| Control | 77 ± 3 | 101 ± 4 | 6.1 ± 0.3 | 5.9 ± 0.3 | 17.7 ± 0.8 | 4.6 ± 0.1 | 4.2 ± 0.2 | 17.0 ± 0.2 |
| AVP | 98 ± 2 | 127 ± 3 | 7.1 ± 1.3 | 7.3 ± 1.3 | 28.6 ± 1.6† | 4.9 ± 0.1 | 2.8 ± 0.1* | 15.7 ± 0.2 |
Values are means ± SE; n = 6 mice. AVP, arginine vasopressin.
*
P < 0.05 and
†
P < 0.001 vs. control.