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. 2016 Mar 10;120(10):1124–1131. doi: 10.1152/japplphysiol.00643.2015

Table 2.

Diaphragm twitch characteristics and maximum force from 4- and 12-wk-old mice

4-wk-old
12-wk-old
Diaphragm 25 IU/kg 10,000 IU/kg 25 IU/kg 10,000 IU/kg
Po, N/cm2 14.8 ± 0.98* 21.6 ± 0.89 18.3 ± 0.98 19.5 ± 0.98
Pt, N/cm2 2.89 ± 0.28 3.93 ± 0.14 3.28 ± 0.38 3.63 ± 0.22
TPT, ms 24.4 ± 1.27 27.5 ± 1.01 23.1 ± 0.91 25.8 ± 1.71
RT1/2, ms 55.0 ± 5.0 66.3 ± 7.31 57.8 ± 4.46 53.8 ± 3.80

Data are from animals fed diets containing 25 or 10,000 IU/kg of vitamin D for 6 wk. Mice were started on the vitamin D diets beginning at 4 and 12 wk of age (n = 5/group, 20 total). Values are means ± SE. Po, maximal tetanic force; Pt, peak twitch force; TPT, time to peak tension; RT1/2, time it takes for peak tetanic force to decrease by 50%.

*

Significantly different from 4-wk 10,000 IU/kg (P = 0.001).