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. 2016 Mar 11;310(9):G726–G738. doi: 10.1152/ajpgi.00436.2015

Fig. 6.

Fig. 6.

High-resolution/accurate-tandem mass spectrometry of individual phospholipid classes. A: principal component analysis of targeted lipidomics. B: heat map representing fold change of each lipid class relative to the mean in control-fed WT mice. LPC, Lyso-PC; LPE, Lyso-PE. C: ion abundance of individual phospholipid species and fatty acid composition. Lipid signals were normalized to synthetic internal standards PC (14:0/14:0), PE (14:0/14:0), and PS (14:0/14:0). UNSAT, unsaturated fatty acid; SAT, saturated fatty acid; PUFA, polyunsaturated fatty acid; MUFA, monounsaturated fatty acid. Values represent means ± SE, n = 4–5. *P < 0.05 vs. WT mice on the control diet. @P < 0.05 vs. WT mice on the MCD diet. #P < 0.05 vs. L-KO mice on the control diet.