Fig. 5.

Sdf1 ASO decreases liver regeneration. Top: hepatocyte proliferation (%PCNA⁺ cells) on day 2 after partial hepatectomy. Bottom: liver weight on day 5. Arrow indicates approximate liver weight after partial hepatectomy, and gray area indicates liver weight regained after partial hepatectomy. Control, liver weights of littermates. Compared with scrambled ASO controls, sdf1 ASO decreases the percentage of PCNA⁺ hepatocytes (*P < 0.025), decreases liver weight (**P < 0.001), and reduces restoration of liver weight (gray shaded area) by 24% (P < 0.001). Values are means ± SE (n = 3).