Fig. 2.

Increased blood pressure (BP) in female Efnb3 KO mice. BP and heart rate (HR) of male (A) and female (B) KO and WT mice were measured by radiotelemetry starting at least 7 days after transmitter implantation. Number per group and the mean ages of the mice at the time of BP measurement are indicated. The BP and HR of all mice were measured for 72 h. Means ± SE of hourly BP and HR are plotted. MAP, mean arterial pressure; SP, systolic pressure; DP, diastolic pressure; HR, heart rate. The 72-h values were used for statistical analysis (ANOVA). P values are indicated.