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The mechanistically diverse PF03099 lipoyl metabolism enzymes. (A) The lipoate ligase reaction catalyzed by B. subtilis LplJ and the LplA proteins of E. coli and S. coelicolor. (B) The octanoyltransferase reaction catalyzed by E. coli LipB and B. subtilis LipM. (C) The amidotransferase reaction catalyzed by the LipL proteins of B. subtilis and L. monocytogenes.
