Table 2.

Comparison between freely perfused and ligated rats of absolute and relative reductions of the pressor response to intermittent contractions caused by GsMTx4

	Freely Perfused (n = 9)	Ligated (n = 9)	P Value
ΔMAP total area, mmHg·s	−190 ± 33	−316 ± 21	0.046*
ΔMAP total area, %	−55 ± 8	−57 ± 3	0.462
ΔMAP s 1–10 area, mmHg·s	−44 ± 13	−105 ± 9	0.032*
ΔMAP s 1–10 area, %	−38 ± 12	−55 ± 6	0.221
ΔMAP s 11–20 area, mmHg·s	−71 ± 13	−110 ± 8	0.093
ΔMAP s 11–20 area, %	−59 ± 7	−53 ± 3	0.317
ΔMAP s 21–30 area, mmHg·s	−75 ± 13	−102 ± 7	0.151
ΔMAP s 21–30 area, %	−66 ± 8	−58 ± 3	0.248
ΔMAP peak, mmHg	−9 ± 2	−15 ± 1	0.098
ΔMAP peak, %	−43 ± 6	−52 ± 4	0.276

Values are means ± SE for freely perfused and ligated rats of the absolute (mmHg or mmHg·s) and relative (%) reductions of the pressor response to intermittent contractions caused by GsMTx4. In the control condition both the total pressor area (freely perfused 361 ± 61, ligated 535 ± 21 mmHg·s, P = 0.034) and the peak pressor (freely perfused 23 ± 2, ligated 29 ± 2 mmHg, P = 0.044) were greater in ligated rats than they were in freely perfused rats. TTIs for intermittent contraction were not different (P > 0.05) between conditions (control vs. GsMTx4) or across groups (freely perfused vs. ligated). Freely perfused data are from our recent publication (9), with 1 rat added to that sample to increase the statistical power of the comparison to ligated rats.

^*P < 0.05.