Table 1.

Baseline parameters of 12-wk-old male mice

Parameter	Control	MSEW
Body weight, g	25.7 ± 2.16	26.0 ± 1.58
Heart weight, g	0.13 ± 0.01	0.14 ± 0.02
Kidney weight, g	0.15 ± 0.02	0.15 ± 0.02
Blood glucose, mg/dl	208 ± 23	210 ± 34
12-hour mean arterial pressure, mmHg
Active period	120.7 ± 1.2	123.0 ± 1.0
Inactive period	108.5 ± 0.9	108.7 ± 1.2
12-hour systolic pressure, mmHg
Active period	135.2 ± 1.6	139.3 ± 1.2
Inactive period	123.2 ± 1.9	122.6 ± 1.9
12-hour diastolic pressure, mmHg
Active period	106.3 ± 0.7	106.7 ± 2.8
Inactive period	93.8 ± 0.8	93.3 ± 2.6
12-hour heart rate, beats/min
Active period	605 ± 11	601 ± 4
Inactive period	567 ± 14	557 ± 6
12-hour activity, counts/min
Active period	15.6 ± 1.4	14.5 ± 3.5
Inactive period	4.1 ± 1.1	3.5 ± 1.1

Values are means ± SE. An unpaired, two-tailed t-test was performed for each parameter: n = 5–8 mice/group for body weight, heart weight, kidney weight, and blood glucose, and n = 4 mice/group for blood pressure, heart rate, and activity.

MSEW, maternal separation with early weaning.