Table 6:
Perioperative outcomes and tumour characteristics after propensity matching
| Characteristics | Open approach (n = 30) | VATS approach (n = 30) | P-value |
|---|---|---|---|
| 30-day mortality (n, %) | 2 (7) | 1 (3) | 0.55 |
| Overall morbiditya (n, %) | 17 (57) | 12 (40) | 0.20 |
| Postoperative bleeding requiring blood transfusion (n, %) | 3 (10) | 2 (7) | 0.64 |
| Postoperative bleeding requiring reoperation (n, %) | 1 (3) | 1 (3) | 1.00 |
| Pneumonia (n, %) | 4 (13) | 2 (7) | 0.39 |
| Atrial fibrillation (n, %) | 7 (23) | 7 (23) | 1.00 |
| Prolonged air leaks (n, %) | 6 (20) | 3 (10) | 0.28 |
| Respiratory failure (n, %) | 1 (3) | 0 (0) | 0.31 |
| Other major complications (n, %) | 6 (9) | 20 (10) | 1.00 |
| Length of hospitalization (days), median (IQR) | 5 (4–8) | 4 (3–5) | 0.007 |
| Chest tube duration (days), median (IQR) | 4 (3–5) | 3 (2–3) | 0.023 |
| Complete pathological response (n, %) | 7 (23) | 6 (20) | 0.75 |
| Preinduction therapy tumour sizeb (cm), mean ± SD | 5.2 ± 3.0 | 4.4 ± 2.8 | 0.38 |
| Postinduction therapy tumour size (cm), mean ± SD | 3.2 ± 2.7 | 3.3 ± 2.5 | 0.89 |
| Down-staged from PN2 to PN0c (n, %) | 7 (50) | 10 (71) | 0.25 |
| Down-staged from PN2 to PN1 or PN0c (n, %) | 8 (57) | 11 (79) | 0.26 |
| Overall down-stagedd (n, %) | 15 (54) | 17 (63) | 0.48 |
VATS: video-assisted thoracoscopic surgery; SD: standard deviation; IQR: interquartile range.
aOverall morbidity represents the number (%) of patients with at least one postoperative complication.
bData only available for 37 of 60 patients (open n = 16, VATS n = 21).
cDenominator used is the number of patients who had N2 disease in the open (n = 14) and VATS (n = 14) groups.
dData only available for 55 of 60 patients (open n = 28, VATS n = 27).