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. 2016 Feb 27;16(2):e34420. doi: 10.5812/hepatmon.34420

Figure 1. Persistence of HBV Markers (HBsAg, HBeAg, HBsAb and HBV DNA) After HI in Sera of Infected Mice.

Figure 1.

A volume of 15 μg of HBV plasmid DNA (pcDNA3.1 (+)-HBV1.3C, pAAV-HBV1.3C or pAAV-HBV1.2A) was injected into the tail veins of male C57BL/6 mice. Each group included 13 mice. At indicated time points, HBsAg, HBeAg and HBsAb in sera were measured by enzyme-linked immunosorbent assay. The HBV DNA in sera was detected by real-time polymerase chain reaction (A, C, D); A, Titer of sera HBsAg; C, HBsAb; E, HBeAg (OD value) in mice after hydrodynamic injection (HI); B, The positive rate of HBsAg; D, or HBsAb; F, in mice after HI. Sera HBV DNA in mice, after HI, and expressed as the l g copies/mL. The results are shown as mean ± SD.