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JAK 1/3 inhibition prevents cancer-mediated diaphragm weakness. Specific force-frequency relationship in diaphragm muscle strips of control mice or cachectic C26 mice fed standard chow or chow containing the JAK 1/3 inhibitor R548. Data represent means ± SE; n = 5 or 6 per group. *P < 0.05 C26/Veh vs. all other groups. **P < 0.05 C26/Veh vs. C26/R548. #P < 0.05 C26/R548 vs. all other groups.
