. 2016 Mar 5;7(5):454–459. doi: 10.1021/acsmedchemlett.5b00468

Table 1. SAR of Compounds 4–8^a^,¹⁸.

IC₅₀ and EC₅₀ values in μM. Compound 3 was used as standard reference compound (see data in Supplementary Table 1).

IC₅₀ and EC₅₀ values are the average of at least three individual measurements ± SD.

SI: selectivity index (HeLa class I HDAC (μM)/Pfgrowth (μM)).

Table 1. SAR of Compounds 4–8a,18.