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. 2016 Mar 5;7(5):454–459. doi: 10.1021/acsmedchemlett.5b00468

Table 2. SAR of Compounds 7 and 14–30a.

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a

IC50 and EC50 values in μM. Compound 3 was used as standard reference compound (see data in Supplementary Table 1).

b

IC50 and EC50 values are the average of at least three individual measurements ± SD.

c

SI: selectivity index (HeLa class I HDAC(μM)/Pfgrowth(μM)).