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. 2016 Mar 21;7(5):537–542. doi: 10.1021/acsmedchemlett.6b00113

Table 1. Cytotoxicity against Cultured Human Prostate Cancer Cellsa.

  LNCaP Cells
PC-3 Cells
Drug IC50(μM) IC90(μM) IC50(μM) IC90(μM)
Enigmol 11.7 ± 1.10 19.6 ± 1.10 12.1 ± 1.02 14.0 ± 1.00
CF3-Enigmol 11.3 ± 1.10 19.2 ± 1.30 21.4 ± 1.17 24.4 ± 1.20
CF2-Enigmol 13.4 ± 1.07 16.7 ± 1.20 11.7 ± 1.05 15.3 ± 1.10
a

LNCaP or PC-3 cells were incubated with compound for 24 h (n = 3–4), and viability was assessed using WST-1. Data represent the mean ± SEM.