Table 2.

Correlation of HAS1 and HAS2 with clinical and histopathological factors

Variable	HAS1 Coverage	HAS1 Intensity	HAS2 Coverage	HAS2 Intensity
Stage	p = 0.006	ns	ns	p = 0.047
pT1, pT4 or pN1-
Melanoma related death	p = 0.007	ns	p = 0.001	p = 0.016
Recurrence	p = 0.021	ns	p = 0.007	ns
Regional recurrence	p = 0.006	p = 0.023	p = 0.007	ns
Distant recurrence	p = 0.012	ns	p = 0.001	p = 0.004
Genre	ns	ns	ns	ns
Age	ns	ns	ns	ns
Ulceration	ns	ns	ns	ns
TIL (low / moderate / high)	ns	ns	p = 0.036	p = 0.040
Mitotic count (mitosis/mm2)	ns	ns	ns	p = 0.018
Horizontal diameter of melanoma (mm)	ns	ns	p = 0.002	p =0.042
Growth type
Nodular	ns	ns	ns	p = 0.001

Stage = pT1, pT4 or pN1-. TIL = tumor-infiltrating lymphocytes (evaluated either low, moderate or high amount). Mitosis = mitosis/mm2, horizontal tumor diameter (mm)