Figure 3.

Kaplan–Meier survival curves demonstrating the self‐reported onset (in years) of nyctalopia (A) or other visual symptoms (B) in males affected by choroideremia. Subjects are grouped by the causative mutation: subjects with missense mutations (labeled; median age of onset of nyctalopia = 10 years, n = 7; median age of onset of other symptoms = 17.5 years, n = 6), subjects who do not express any Rab escort protein 1 due to whole gene deletions or deletions of the ATG start codon (median age of onset of nyctalopia = 11 years, n = 5; median age of onset of other symptoms = 20 years, n = 5), and subjects with other disease causing mutations (median age of onset of nyctalopia = 10.5 years, n = 58; onset of other symptoms = 17.5 years, n = 60). There is no significant difference between the survival curves of the three groups (nyctalopia: P = 0.08; other visual symptoms: P = 0.35).