Figure 6.

The visual field (the continuous visual field across the horizontal meridian, in degrees) of affected males' better eye as a function of age (n = 64). The sample population was divided at the critical age (20 years old), separating individuals into the ≤20 years old group and the >20 years old group. Individuals with missense mutations are indicated by an orange + and labeled; individuals who do not express any Rab escort protein 1 due to whole gene deletions or deletions of the ATG start codon are indicated by a blue ×. In a linear regression model (green line), age was not a significant predictor of visual field in the ≤20 years old group (P = 0.785); the rate of change of visual fields in the >20 years old group is a loss of 0.868 horizontal degrees per year (P = 0.005).