Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 16;6:25979. doi: 10.1038/srep25979

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Values are mean ± S.E.M. for the concentration-response curve maximal response and sensitivity to sodium nitroprusside (SNP) and methacholine in femoral arteries of 12 week old WT (○, W12, n = 9), 12 week old R6/2 (●, R12, n = 9), 16 week old WT (, W16, n = 9) and 16 week old R6/2 (, R16, n = 7) mice. Concentration-response curves were analysed using an agonist-response best-fit line. The maximal relaxant response (%PE_max) was expressed as percentage of the contraction induced by phenylephrine and the vascular sensitivity was expressed as pD₂ (−logEC₅₀). Different letters, a and b, represent significantly different responses between groups, P < 0.05. Two-way ANOVA with post-hoc Bonferroni Test.

Inline graphic — Values are mean ± S.E.M. for the concentration-response curve maximal response and sensitivity to sodium nitroprusside (SNP) and methacholine in femoral arteries of 12 week old WT (○, W12, n = 9), 12 week old R6/2 (●, R12, n = 9), 16 week old WT (, W16, n = 9) and 16 week old R6/2 (, R16, n = 7) mice. Concentration-response curves were analysed using an agonist-response best-fit line. The maximal relaxant response (%PE_max) was expressed as percentage of the contraction induced by phenylephrine and the vascular sensitivity was expressed as pD₂ (−logEC₅₀). Different letters, a and b, represent significantly different responses between groups, P < 0.05. Two-way ANOVA with post-hoc Bonferroni Test.