Table 3. Gene Ontology (GO) enrichment analysis of up-and down-regulated genes in C. finmarchicus feeding on low (LD) and high dose (HD) treatments of A. fundyense for 2 days.
| Time/treatment | Term description | GO | Category | FDR |
|---|---|---|---|---|
| 2 days LD | ||||
| Up regulated | ||||
| RNA biosynthetic process | GO:0032774 | BP | 5.16E-03 | |
| Cellular macromolecule biosynthetic process | GO:0034645 | BP | 3.01E-03 | |
| Cellular protein metabolic process | GO:0044267 | BP | 4.73E-02 | |
| Macromolecular complex | GO:0032991 | CC | 3.01E-02 | |
| Heterocyclic compound binding | GO:1901363 | MF | 3.01E-02 | |
| Organic cyclic compound binding | GO:0097159 | MF | 3.01E-02 | |
| Peptidase activity | GO:0008233 | MF | 3.93E-02 | |
| Transferase activity | GO:0016740 | MF | 1.10E-02 | |
| Cytoplasmic part | GO:0044444 | CC | 2.46E-02 | |
| Intracellular membrane-bounded organelle | GO:0043231 | CC | 3.42E-03 | |
| 2 days HD | ||||
| Up regulated | ||||
| Lipid metabolic process | GO:0006629 | BP | 4.62E-02 | |
| RNA biosynthetic process | GO:0032774 | BP | 1.58E-03 | |
| Translation | GO:0006412 | BP | 4.62E-02 | |
| Macromolecular complex | GO:0032991 | CC | 2.25E-02 | |
| Nucleic acid binding | GO:0003676 | MF | 1.91E-03 | |
| Nucleotide binding | GO:0000166 | MF | 3.79E-02 | |
| Signal transduction | GO:0007165 | BP | 1.55E-02 | |
| Cytosol | GO:0005829 | CC | 2.91E-02 | |
| Extracellular region | GO:0005576 | CC | 5.75E-03 | |
| Nucleus | GO:0005634 | CC | 1.23E-03 | |
| Down regulated | ||||
| Cellular metabolic process | GO:0044237 | BP | 2.48E-02 | |
| Single-organism cellular process | GO:0044763 | BP | 2.88E-02 | |
Gene ontology term (GO); Category: Biological process (BP), Molecular function (MF) and Cellular component (CC); false discovery rate (FDR) after Fisher exact test using FDR <5% as cutoff.