Table 1. Clinicopathologic characteristics of the 297 patients.
Parameter | Number of patients | Percent (%) |
---|---|---|
Age, mean (range), yrs: 41.4 ± 8.6 (22–74) | ||
≤45 | 207 | 69.7 |
>45 | 90 | 30.3 |
Tumor sizea, mean (range), cm: 1.2 ± 0.6 (0.2–2.0) | ||
Stage | ||
Ia2 | 50 | 16.8 |
Ib1 | 247 | 83.2 |
Histology | ||
SCCb | 279 | 93.9 |
ADc | 16 | 5.4 |
ASCd | 2 | 0.7 |
Grade | ||
1 | 79 | 26.6 |
2 | 136 | 45.8 |
3 | 82 | 27.6 |
Conization parameter | ||
Conization | ||
LEEPe | 40 | 13.5 |
CKCf | 257 | 86.5 |
Tumor width, mean (range), mm: 12.98 ± 7.7 (0.2–4.0) | ||
≤20 mm | 262 | 88.2 |
>20 mm | 35 | 11.8 |
Depth of stromal invasion, mean (range), mm: 4.1 ± 2.3 (1.0–13.0) | ||
≤5 mm | 237 | 79.8 |
>5 mm | 60 | 20.2 |
LVSIg | 47 | 15.8 |
Positive RMh | 155 | 52.2 |
Ectocervical RM | 48 | 16.2 |
Endocervical RM | 103 | 34.7 |
Deep RM | 51 | 17.2 |
RHi parameter | ||
Surgical approach | ||
Laparotomy | 168 | 56.6 |
Laparoscopy | 129 | 43.4 |
Residual disease | 97 | 32.7 |
Carcinoma in situ | 23 | 23.7 |
Invasive cancer | 74 | 76.2 |
Tumor width, mean (range), mm: 14.0 ± 8.4 (0.2–4.0) | ||
≤20 mm | 233 | 78.5 |
>20 mm | 64 | 21.5 |
Depth of stromal invasion, mean (range), mm: 4.6 ± 2.4 (1–15) | ||
≤5 mm | 215 | 724 |
>5 mm | 82 | 27.6 |
LVSI | 48 | 16.2 |
Vaginal invasion | 4 | 1.3 |
Parametrial invasion | 2 | 0.6 |
LNMj | 15 | 5.1 |
Pelvic | 13 | 4.4 |
Para-aortic | 2 | 0.7 |
Positive RM | 0 | 0 |
aClinically measurable tumors only; bSquamous cell carcinoma; cAdenocarcinoma; dAdenosquamous carcinoma; eCold knife cone; fLoop electrosurgical excision procedure; gLymphovascular space involvement; hResection margin; iRadical hysterectomy; jLymph node metastasis.