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. 2016 May 16;6:25918. doi: 10.1038/srep25918

Figure 1. The deregulation of SOD2 in the development of SACC tissue.

Figure 1

Immunohistochemical analyses for SOD2 expression were performed in normal salivary gland (A) and SACC samples (B). (Scale bar: 50 μm) Box plots compare the expression of SOD2 between 20 normal salivary glands and 50 SACC samples (C), P = 0.000), and SACC with (n = 8) or without (n = 42) distant metastasis (D), P = 0.000). Boxes represent the 25th and 75th percentiles. The lines in the middle of the box represent medians. *P < 0.001. Patients were divided into SOD2 low expression group (n = 28) and SOD2 high expression group (n = 22). The 5-year overall survival rate (E), P = 0.017) and 5-year disease-free survival rate (F), P = 0.038) were significantly higher in SOD2 low expression group. *P < 0.05. Student’s T test was used to compare the difference between groups (C,D). Survival curves were plotted using the Kaplan-Meier method and compared with the log-rank test (E,F).