Figure 1. The effects of a single exercise bout on total T-cell numbers and CD8+ T-cell subset composition in response to viral-peptide stimulation over 8-days.

PBMCs (10 × 10⁶) isolated before or after exercise were simultaneously stimulated with CMV pp65, CMV IE-1, EBV LMP-2 and EBV BMLF-1 peptides in the presence of IL-4 and IL-7. IL-15 was subsequently added at Day 4. Statistically significant difference from Day 0 indicated by (*p < 0.05). Statistically significant difference between the before (PRE) and after (POST) exercise conditions indicated by (#p < 0.05). Naïve (NA; CD45RA+/CD62L+), central memory (CM; CD45RA−/CD62L+), effector-memory (EM; CD45RA−/CD62L−) and RA+ effector-memory (EMRA; CD45RA+/CD62L−) T-cells.