Table 2. Significant associations with global DNA methylation (dependent variable) in the AMM subjects.
| Sample | Variable | Beta | t | p | adjusted R2 |
|---|---|---|---|---|---|
| PD | PUFAs | 0.0214 | 3.7356 | 0.0047 | 0.4815¶ |
| BMI | −0.1611 | −3.1200 | 0.0268 | 0.7437§ | |
| glucose | 0.0849 | 3.2093 | 0.0237 | ||
| C20:4 (AA) | 0.1118 | 4.2941 | 0.0013 | ||
| C20:5 (EPA) | 0.7000 | 6.1371 | 0.0001 | ||
| FD | PUFAs | 0.0146 | 2.5549 | 0.0309 | 0.4273¶ |
| BMI | −0.0862 | −2.9481 | 0.0163 | 0.6235§ | |
| C20:5 (EPA) | 1.1339 | 4.2449 | 0.0017 |
¶SFA/MUFA/PUFA model.
§Individual PUFA model. Beta values indicate the change in % 5mdC per one-point increase in FA (%), BMI or glucose (mg/dl). Non-significant associations are shown in Supplementary Table 2.4.