Table 1.

Cardiometabolic profile of ND‐ and HFD‐fed mice

Metabolic parameters	ND	HFD
Body weight (g)	30.2 ± 0.7	48.3 ± 0.4*
Glucose (mM)	8.5 ± 0.6	11.4 ± 0.8*
Insulin (pg·mL−1)	1364.7 ± 293.2	4053.3 ± 518.4*

Echocardiographic parameters	ND	HFD
IVST, cm	0.08 ± 0.01	0.10 ± 0.01*
LVID, cm	0.37 ± 0.01	0.39 ± 0.01
LVPWT, cm	0.08 ± 0.01	0.10 ± 0.01*
EF, %	79.15 ± 2.73	69.23 ± 0.889*
FS, %	39.43 ± 1.35	33.59 ± 0.63*

Body weight, plasma levels of glucose and insulin, interventricular septum thickness (IVST), left ventricular internal diameter (LVID), left ventricular posterior wall thickness (LVPWT), fractional shortening (FS) and ejection fraction (EF) were measured in mice fed a ND or HFD for 6 months. Data are means ± SEM; n = 5–6 per group.

^* P < 0.05 versus ND‐fed group.