Table 3. Analysis of buried surface areas.
SEA-hTRBV7-9 (B:C)*Residue BSA | SEE-hTRBV7-9 (B:C)*Residue BSA | SEB-mTRBV13-2 (A:B)*Residue BSA | SEC3-mTRBV13-2 (A:B)*Residue BSA | SEH-hTRAV27 (A:C)*Residue BSA | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% | Å2 | % | Å2 | % | Å2 | % | Å2 | % | Å2 | |||||
Asn25 | 96 | 35 | Asn21 | 99 | 68 | Leu20 | 94 | 77 | Thr20 | 93 | 47 | Asn16 | 85 | 25 |
Tyr32 | 62 | 85 | Asn25 | 97 | 30 | Asn23 | 93 | 49 | Asn23 | 89 | 55 | Gly19 | 95 | 22 |
Trp63 | 92 | 163 | Gln28 | 97 | 62 | Tyr91 | 48 | 88 | Phe174 | 85 | 118 | Tyr79 | 71 | 83 |
Tyr94 | 63 | 93 | Trp63 | 90 | 153 | Phe177 | 93 | 99 | ||||||
Phe175 | 76 | 113 | Tyr94 | 73 | 95 | |||||||||
Phe175 | 75 | 126 | ||||||||||||
Pro206 | 89 | 14 |
Residues in the SAgs that have a buried surface area of ≥85% and/or of ≥80 Å2 upon complex formation according to the PDBePISA server. *Chain ID of the structure models that were used for the interface analysis. The conserved asparagine and the hydrophobic pair are underlined.