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. 2016 May 14;13:35. doi: 10.1186/s12986-016-0092-z

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© Koochakpoor et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Adjusted OR for abdominal obesity to quartile of iron intake by MC4R genotypes (p interaction = 0.002). Q1 < 13.88 mg, Q2 = 13.88–15.98 mg, Q3 = 15.98–40.36 mg, Q4 > 40.36 mg. Among other nutrients (iron, zinc and magnesium), iron has an interaction with this SNP in the development of abdominal obesity (P interaction = 0.006); in A allele carriers, the risk of abdominal obesity did not change significantly with increased iron consumption (P trend = 0.50) but for GG genotype carriers, more consumption of iron led to an increase in risk of abdominal obesity (P trend = 0.002)