Table 1.
Baseline characteristics of the patient population
| Study group (n = 33) |
Control group (n = 29) |
P value | |
|---|---|---|---|
| Age, mean (years) | 62.2 | 57.9 | 0.367 |
| Female sex | 12 (36.4 %) | 12 (41.4 %) | 0.686 |
| Body mass index (kg/m2), mean | 22.3 | 22.1 | 0.826 |
| Hypertension | 11 (33.3 %) | 8 (27.6 %) | 0.624 |
| Diabetes mellitus | 8 (24.2 %) | 6 (20.7 %) | 0.739 |
| Ischemic heart disease | 0 (0 %) | 1 (3.4 %) | 0.282 |
| Chronic renal failure | 3 (9.1 %) | 2(6.9 %) | 0.752 |
| Angiotensin converting enzyme inhibitor | 5 (15.2 %) | 4 (13.8 %) | 0.880 |
| Angiotensin receptor blocker | 0 (0 %) | 1 (3.4 %) | 0.282 |
| Beta blocker | 6 (18.2 %) | 1 (3.4 %) | 0.067 |
| Calcium channel blocker | 7 (21.2 %) | 3 (10.3 %) | 0.246 |
| Diuretic | 1 (3 %) | 1 (3.4 %) | 0.926 |
| Statin | 2 (6.1 %) | 4 (13.8 %) | 0.304 |
| Oxygen saturation, % | 97.7 % | 97.7 % | 0.919 |
| Body temperature (oC), mean | 37.3 | 37.5 | 0.195 |
| Glasgow coma scale, mean score | 11.8 | 15 | <0.001* |
| Bacteremia | 15 (45.5 %) | 3 (10.7 %) | 0.027* |
| - Gram positive | 2 (6.1 %) | 0 (0 %) | |
| - Gram negative | 12 (36.4 %) | 3 (10.7 %) | |
| - Others | 1 (3 %) | 0 (0 %) | |
| Renal replacement therapy | 4 (12.1 %) | 0 (0 %) | 0.053* |
| Mechanical ventilation | 17 (51.5 %) | 0 (0 %) | <0.001* |
| - Non-invasive ventilation | 1 (3 %) | 0 (0 %) | |
| - Invasive mechanical ventilation | 16 (48.5 %) | 0 (0 %) | |
| SOFA score, mean | 10.2 | 1.6 | <0.001* |
Results are presented as number of patients (percentage within group in parentheses) unless stated otherwise. SOFA sequential organ failure assessment. *P < 0.05