Table 2.
Associations of IFITM1 expression in primary tumors with clinicopathological data
| Factor | Entire cohort median (range) | p-value | Esophagus median (range) | p-value | GE junction median (range) | p-value | Stomach median (range) | p-value |
|---|---|---|---|---|---|---|---|---|
| Age | ||||||||
| ≤ average >average |
1.75 (0.00-10.50) 2.00 (0.00-12.00) |
0.103 | 2.00 (0.00-10.50) 1.00 (0.00-7.50) |
0.363 | 2.50 (0.00-9.80) 2.50 (0.00-12.00) |
0.693 | 0.00 (0.00-9.00) 2.50 (0.00-12.00) |
0.001 |
| Sex | ||||||||
| Female Male |
2.50 (0.00-11.00) 1.00 (0.00-12.00) |
0.207 | 4.00 (1.00-6.50) 1.00 (0.00-10.50) |
0.080 | 2.50 (0.00-6.50) 2.00 (0.00-12.00) |
1.000 | 2.00 (0.00-11.00) 1.00 (0.00-12.00) |
0.588 |
| T-stage | ||||||||
| T1 T2 T3 T4 |
1.75 (0.00-10.00) 2.00 (0.00-12.00) 1.75 (0.00-12.00) 1.00 (0.00-12.00) |
0.805 | 2.00 (0.00-8.00) 2.25 (0.00-7.50) 1.25 (0.00-9.80) 0.50 (0.00-7.00) |
0.400 | 1.75 (0.00-3.50) 0.50 (0.00-4.00) 2.50 (0.00-12.00) 2.50 (2.00-8.00) |
0.669 | 1.00 (0.00-10.00) 3.00 (0.00-12.00) 1.25 (0.00-11.00) 1.00 (0.00-12.00) |
0.883 |
| N-stage | ||||||||
| N0 N1 N2 N3 |
2.00 (0.00-12.00) 2.00 (0.00-12.00) 1.00 (0.00-12.00) 1.75 (0.00-10.50) |
0.585 | 2.25 (0.00-8.00) 2.00 (0.00-6.50) 0.75 (0.00-9.80) 1.50 (0.00-10.50) |
0.471 | 2.50 (0.00-12.00) 3.00 (0.00-11.00) 1.25 (0.00-8.00) 2.75 (0.00-9.80) |
0.694 | 1.25 (0.00-12.00) 2.50 (0.00-12.00) 2.00 (0.00-12.00) 0.50 (0.00-6.00) |
0.504 |
| M-stage | ||||||||
| M0 M1 |
2.00 (0.00-12.00) 0.50 (0.00-6.50) |
0.033 | 1.75 (0.00-10.50) 1.25 (0.00-5.50) |
0.528 | 2.50 (0.00-12.00) 2.00 (0.00-6.50) |
0.693 | 2.00 (0.00-12.00) 0.00 (0.00-2.00) |
0.011 |
| R-classification | ||||||||
| R0 R1 R2 |
2.00 (0.00-12.00) 1.00 (0.00-9.80) 0.00 (0.00-10.00) |
0.055 | 2.00 (0.00-10.50) 1.00 (0.00-9.80) 0.00 (0.00-0.00 |
0.444 | 3.00 (0.00-12.00) 2.00 (0.00-7.00) 0.125 (0.00-0.30) |
0.252 | 2.00 (0.00-12.00) 0.50 (0.00-4.50) 0.25 (0.00-10.00) |
0.225 |
| Differentiation grade | ||||||||
| High Intermediate Low |
2.00 (0.00-3.00) 2.00 (0.00-12.00) 1.50 (0.00-12.00) |
0.759 | 2.00 (1.00-2.00) 2.00 (0.00-10.50) 1.00 (0.00-8.00) |
0.629 | 2.50 (2.50-2.50 1.50 (0.00-5.50) 2.50 (0.00-12.00) |
0.586 | 0.50 (0.00-3.00) 3.00 (0.00-12.00) 1.00 (0.00-12.00) |
0.324 |
| Lauren classification | ||||||||
| Intestinal Mixed Diffuse |
2.00 (0.00-12.00) 1.00 (0.00-6.50) 0.50 (0.00-12.00) |
0.150 | 1.75 (0.00-10.50) 1.875 (0.00-6.50) 0.00 (0.00-0.00) |
0.191 | 2.00 (0.00-12.00) 3.00 (0.00-3.00) 3.50 (0.00-12.00) |
0.565 | 3.00 (0.00-12.00) 0.25 (0.00-0.50) 0.38 (0.00-10.00) |
0.008 |
| Intestinal metaplasia background | ||||||||
| No Yes |
1.00 (0.00-12.00) 2.25 (0.00-12.00) |
0.083 | 1.00 (0.00-10.50) 2.00 (0.00-7.00) |
0.446 | 2.00 (0.00-12.00) 4.25 (0.00-12.00) |
0.090 | 0.75 (0.00-12.00) 1.75 (0.00-12.00) |
0.271 |
| Location | ||||||||
| Esophagus GE junction Stomach |
1.50 (0.00-10.50) 2.50 (0.00-12.00) 1.00 (0.00-12.00) |
0.829 |