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. 2016 May 14;4:10. doi: 10.1186/s40364-016-0064-5

Table 3.

Hazard ratios for recurrence and death M0 R0-1

Time to recurrence
Unadjusted Adjusteda
n (events) HR (95 % CI) p-value HR (95 % CI) p-value
Esophagus
 IFITM1
  Low
  High
23 (13)
16 (9)
1.00
1.09 (0.47-2.56)
0.836 1.00
3.05 (1.09-8.53)
0.034
GE junction
 IFITM1
  Low
  High
16 (10)
17 (10)
1.00
1.09 (0.45-2.62)
0.852 1.00
1.50 (0.59-3.82)
0.400
Stomach
 IFITM1
  Low
  High
30 (19)
20 (5)
1.00
0.33 (0.12-0.88)
0.026 1.00
0.32 (0.12-0.87)
0.026
Overall survival
Unadjusted Adjustedb
n (events) HR (95 % CI) p-value HR (95 % CI) p-value
Esophagus
 IFITM1
  Low
  High
31 (20)
18 (11)
1.00
0.99 (0.47-2.07)
0.976 1.00
2.71 (1.11-6.67)
0.029
GE junction
 IFITM1
  Low
  High
19 (15)
19 (16)
1.00
1.00 (0.49-2.03)
0.995 1.00
0.97 (0.44-2.15)
0.937
Stomach
 IFITM1
  Low
  High
32 (22)
24 (15)
1.00
0.83 (0.43-1.62)
0.592 1.00
0.80 (0.39-1.64)
0.539

aAdjusted for: T-stage, N-stage, R-classification

bAdjusted for: age, T-stage, N-stage, R-classification, differentiation grade