Results of receiver operating characteristic analysis of characterization of musculoskeletal lesions as malignant on basis of semiquantitative and absolute quantitative metrics.
A and B, Graphs show receiver operating characteristic curves generated in 26 cases with choline signal-to-noise ratio (A) and in 24 cases with absolute choline concentration derived from proton MR spectroscopic data (B). Areas under each curve are large (A, 0.9281; B, 0.9492), allowing threshold choices of 5 for choline signal-to-noise ratio and 0.3 or 0.8 mmol/kg for absolute choline concentration, which are highly sensitive and relatively specific for malignancy (Table 4). Curves generated with Stata 11 software (StataCorp).