Table 1.
Clinical, molecular and immunohistochemical features of glioblastomas (GBMs) vs. glioblastomas with oligodendroglioma component (GBM‐Os)
| Variable | GBM | GBM‐O | P‐value |
|---|---|---|---|
| Average age | 58.7 (± 0.971) years | 50.7 (± 2.761) years | 0.00517 |
| Median age | 60 years | 50 years | |
| Male | 121 | 21 | 0.102 |
| Female | 87 | 7 | |
| MGMT methylated | 58 | 9 | 1 |
| MGMT unmethylated | 70 | 11 | |
| EGFR amplified | 59 | 6 | 0.193 |
| EGFR unamplified | 102 | 20 | |
| PTEN deleted | 93 | 10 | 0.05 |
| PTEN intact | 5 | 3 | |
| p53 positive (IHC) | 48 | 7 | 0.47 |
| p53 negative | 60 | 14 | |
| IDH1 positive (IHC) | 10 | 7 | 0.004 |
| IDH1 negative | 106 | 13 | |
| Primary neoplasm | 191 | 19 | 0.001 |
| Secondary neoplasm | 17 | 9 |