Table 2. Univariate analysis of factors influencing overall survival in resected patients with pancreatic adenocarcinoma from the National Cancer Data Base, 1998 to 2002 (N = 11,526).

Covariate	Level	HR	95 % CI Low	95 % CI High	HR p value
Adjuvant therapy	ChemoRad	1.170	1.120	1.224	<0.001
	ChemoOnly	1.592	1.479	1.714	<0.001
	NoAdjuvant	–	–	–	–
Age at diagnosis	≤50 years	0.606	0.566	0.648	<0.001
	50–65 years	0.780	0.732	0.832	<0.001
	65–75 years	0.856	0.806	0.910	<0.001
	>75 years	–	–	–	–
Gender	Male	1.049	1.006	1.094	0.025
	Female	–	–	–	–
White race	No	0.963	0.902	1.028	0.259
	Yes	–	–	–	–
Median income, 2000	<$30,000	1.166	1.089	1.248	<0.001
	$30,000-$34,999	1.121	1.054	1.191	<0.001
	$35,000-$45,999	1.067	1.013	1.124	0.015
	>$46,000	–	–	–	–
Insurance type	Uninsured	0.900	0.782	1.037	0.146
	Medicaid	0.768	0.678	0.869	<0.001
	Private/other	0.821	0.774	0.871	<0.001
	Medicare	–	–	–	–
Facility type	CCP	1.231	1.144	1.325	<0.001
	CCCP	1.171	1.120	1.224	<0.001
	ARCP	–	–	–	–
Facility volume (unit = 50)		0.943	0.927	0.959	<0.001
Year of diagnosis	1998	1.106	1.036	1.182	0.003
	1999	1.071	1.003	1.143	0.041
	2000	1.038	0.974	1.107	0.252
	2001	1.016	0.954	1.081	0.626
	2002	–	–	–	–
Primary site	Head	1.297	1.122	1.499	<0.001
	Body	1.120	0.946	1.326	0.189
	Tail	0.844	0.720	0.988	0.035
	Body/tail	–	–	–	–
Tumor size	≤25 mm	0.913	0.857	0.973	0.005
	25–35 mm	1.143	1.070	1.221	<0.001
	35–45 mm	1.228	1.142	1.321	<0.001
	>45 mm	–	–	–	–
Stage	I	0.365	0.338	0.394	<0.001
	II	0.606	0.563	0.652	<0.001
	III	0.822	0.773	0.874	<0.001
	IV	–	–	–	–
Grade	Unspecified	0.365	0.339	0.393	<0.001
	I	0.410	0.380	0.443	<0.001
	II	0.764	0.729	0.801	<0.001
	III/IV	–	–	–	–
Surgical margin positive	No	0.654	0.623	0.687	<0.001
	Yes	–	–	–	–
LN positive	No	0.579	0.553	0.606	<0.001
	Yes	–	–	–	–
No. of examined LNs > 12	No	0.958	0.913	1.005	0.076
	Yes	–	–	–	–