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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Crit Care Med. 2015 Aug;43(8):1612–1621. doi: 10.1097/CCM.0000000000001022

table 4.

Description of Adverse Drug Reactions

Description Number (%)
(n = 116)
Hypotension 14(12.07)
Delirium 13(11.21)
Tachycardia 12(10.34)
Hyperglycemia 10(8.62)
Other (e.g., tremor, ototoxicity, and
seizure)
11 (9.46)
Bleeding 8 (690)
Thrombocytopenia 7 (6.03)
Constipation 5 (5.17)
Elevated triglycerides 6 (5.17)
Hypoglycemia 5 (431)
Electrolyte abnormalities (e,g,
hyperkalemia and hypokalemia)
5 (431)
Acute kidney injury 4 (3.45)
Diarrhea 4 (3.45)
Impaired oxygenation/shortness
of breath
4 (3.45)
Rash 4 (3.45)
Nausea 3 (257)

Adverse drug reaction Definitions/Descriptions: hypotension = blood pressure < 90/60mm Hg; delirium = per standardized scale or physician judgment; tachycardia = heart rata > 100 beats/min; hyperpylcemia = blood sugar > 1 80; bleeding = loss of blood or visible signs of bleeding; constipation = < bowel movements in 1 week; elevated triglycerides = triglycerides > 200; hypoglycemia = blood sugar < 70 mg/dL; electrolyte abnormalities = electrolyte readmg outside of the normal range; acute kidney injury = an increase in the serum creatinine by two-fold or a decrease in the glomerular filtration rate 50%, a urine output of < 0.5 mL/kg/hr for 12 hr; diarrhea = three or more watery stools per day; impaired oxygenation/shortness of breath = increase in oxygen requirements, mechanical ventilation support, or patient subjective complaint; rash = a skin eruption that may be accompanied by itching; nausea = a sensation often associated, but not limited to vomiting.