. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Crit Care Med. 2015 Aug;43(8):1612–1621. doi: 10.1097/CCM.0000000000001022

table 6.

Cox Proportional Hazard Regression of Potential Relationships Between Drug Status and Adverse Drug Reactions

Covariate	Hazard Ratio (95% CI)	p
Length of stay	0.911 (0.856–0.969)	0003
No. of medications before ADR	0.897 (0.862–0.934)	< 0.001
No, of high-alert medications received before ADR	1.259(1.127–1.407)	< 0.001
No. of off-label medications before ADR	1.084(1.018–1.154)	0.012

ADR = adverse drug reaction.