Table 6. Association between individual proportion of Western African sub-continental genomic ancestry levels relative to total African ancestry with Trypanosoma cruzi infection and any major electrocardiogram abnormalities among infected (The Bambui-Epigen Cohort Study of Aging).
| Proportion of genomic Western African ancestrya in quintiles | Infected with T. cruzi | Any major ECG abnormality among infected with T. cruzi | ||
|---|---|---|---|---|
| No. (%) | Adjusted PR (95% CI)b | No. (%) | Adjusted PR (95% CI)b | |
| Lowest (<33.3%) | 79 (29.4) | 1.0 | 49 (62.0) | 1.0 |
| 2nd-4th (33.3%-73.3%) | 327 (40.6) | 0.97 (0.79, 1.19) | 187 (57.2) | 0.88 (0.70, 1.10) |
| Highest (≥73.3%) | 99 (36.9) | 0.99 (0.78, 1.26) | 49 (49.5) | 0.80 (0.58, 1.09) |
| p = 0.004 | p = 0.221 | |||
ECG, electrocardiogram; PR (95% CI), prevalence ratio (95% confidence interval) estimated by Poisson regression; p, p value—Pearson´s chi square test.
aRelative to total genomic African ancestry.
bAge, sex, smoking, body mass index, hypertension, diabetes, coronary heart disease, log high sensitivity C-reactive protein and non HDL cholesterol, schooling level, monthly household income per capita and father’s occupation plus cluster in family.