Table 1. Demographic and statistics of clinical assessments at baseline.
Variable | NC group (n = 34) | MCI group (n = 48) | ||
---|---|---|---|---|
NC convert (n = 10) | NC non-convert (n = 24) | MCI convert (n = 24) | MCI non-convert (n = 24) | |
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |
Demographic | ||||
Male/ Female | 9/1 | 17/7 | 14/10 | 20/4 |
Age | 77.4 (3.4) | 74.6 (4.0) | 71.8 (7.0) | 75.7 (7.1) |
Education years | 16.2 (4.1) | 17.0 (3.0) | 16.5 (2.7) | 14.4 (2.8)* |
APOE carriers (%) | 40.0 | 16.7 | 54.2 | 45.8 |
Clinical Measures | ||||
ADAS-cog TOTAL11 | 6.1 (1.4) | 5.9 (2.9) | 11.2 (4.2) | 8.1 (2.8) ** |
ADAS-cog TOTALMOD | 9.9 (2.2) | 8.5 (3.6) | 17.4 (7.2) | 14.2 (4.8)* |
MMSE | 29.0 (0.9) | 28.8 (1.5) | 27.3 (1.8) | 28.2 (1.3) |
CDR | 0 | 0 | 0.5 | 0.5 |
Note: NC: cognitively normal control (NC), MCI: mild cognitive impairment, ADAS-cog: Alzheimer’s Disease Assessment Scale-Cognitive Sub-scale, CDR: clinical dementia rating.
* p<0.05
** p<0.01.