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. Author manuscript; available in PMC: 2016 May 16.
Published in final edited form as: Dev Biol. 2014 Dec 16;399(1):41–53. doi: 10.1016/j.ydbio.2014.12.010

Figure 4. Expression of multipotent pancreatic progenitor markers Sox9, Pdx1, and Aldh1.

Figure 4

(A) Immunofluorescent images showed expression of early pancreatic progenitor markers Pdx1 and Sox9. The expression pattern of Pdx1 was comparable in both wild-type and homozygous p120f/f pancreases throughout development, while the normal downregulation of Sox9 expression failed to occur in the absence of p120 catenin. (B) Immunohistochemical labeling for Aldh1 demonstrated persistent expression in expanded tubular pancreatic epithelium lacking p120 catenin. Scale bars are 50μm.