Fig. 3.

Experiment 1: body weight gain (A) and food intake (B) in DR rats that were sham, control adeno-associated virus (AAV), and AAV containing a short hairpin portion of the calcitonin receptor mRNA (AAV CTR shRNA) injected bilaterally in the ARC and VMN at 4 wk of age and fed chow (13.5% fat) for 6 wk, followed by 6 wk on 45% fat diet. Values are means ± SE. *P ≤ 0.05 when food intake and body weight gain data at a specific time point (on x-axis) in AAV CTR shRNA-injected rats were compared with that in sham and control AAV-injected rats by post hoc Bonferroni test after intergroup differences were found by one-way ANOVA for repeated measures.