Fig. 5.

Experiment 2: ¹²⁵I-labeled leptin binding (A) and leptin-induced phosphorylation of signal transducer and activator of transcription 3 (pSTAT3) immunohistochemistry (B) in the ARC and VMN of DIO sham, DR AAV control, and DR AAV CTR shRNA rats injected at 4 wk of age and fed chow for 6 wk. Values are means ± SE; N = 12/group. ^a,b,c|Data with differing superscripted letters differ from each other by P ≤ 0.05 by post hoc Bonferroni test after intergroup differences were found by one-way ANOVA.