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Effect of physostigmine on encountering a familiar maze again or a novel trajectory. A: change in speed; physostigmine decreased running speed in adult rats more than old rats, although both age groups still slowed down more on the novel trajectory. B: change in theta power; physostigmine increased theta power only in old rats. C and D: there was no effect of either age or environment on low (C) or high (D) gamma power. *P < 0.05.
