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Inhalation of nociceptive stimuli evoke second degree atrioventricular (AV) block. Derived from ECG data recorded during exposure to vehicle, capsaicin (3 mM, blue, n = 3), ATP (30 mM, black, n = 3), and AITC (30 mM, red, n = 11 and 8, respectively). A: mean ± SE AV Block. B: mean ± SE PR interval (PR-I). *Significant difference to vehicle response (P < 0.05).
