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. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: Int J Cardiol. 2015 Jul 12;199:451–459. doi: 10.1016/j.ijcard.2015.07.040

Figure 2. Soluble cardiac biomarkers are differentially expressed in chronic Chagas cardiomyopathy disease stages.

Figure 2

NTproBNP and Troponin were significantly elevated in CC-P and CC-BD compared to seronegative and/or Non-CC BD groups (p<0.005). CKMB was elevated in CC compared to other T. cruzi Ab+ and seronegative donor groups (p<0.05). Myoglobin and VCAM were elevated in CC-P compared to non-CC-BD and seronegative groups (p<0.005). There were reductions in other circulating biomarkers with disease severity; these markers included plasminogen activated inhibitor (PAI-1), myeloperoxidase (MPO) and monocyte chemotactic protein (MCP-1) (p<0.05).