Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Importin 8 transformation activity is eIF4E-dependent. Foci assays in U2OS cells as a function of importin 8 shRNA knockdown (A, shImp8) or importin 8 overexpression (B, FLAG Imp8). shCtrl and FLAG vect indicate corresponding controls. (Right) Foci numbers relative to controls are quantified. Data are the mean ± SD. **P < 0.01; ***P < 0.001. Western blots for FLAG Imp8 and eIF4E expression are shown in Fig. S4A.
