Fig. 1.

In situ proliferation and expression of emerin and lamin A/C in the common carotid artery of hypertensive rats and sham-treated controls. (A) Immunofluorescence staining against BrdU revealed that after 1 wk of abdominal aorta coarctation, VSMC proliferation in the media of common carotid arteries increased markedly. (B) The expression of emerin and of lamin A/C was repressed significantly in the common carotid arteries of the aorta-coarctation–induced hypertensive rats. GAPDH was used for normalization. Values are expressed as mean ± SD. *P < 0.05 vs. the sham-treated control (n = 5).