Fig. 6.

(A and B) Local injection of emerin (A) or lamin A (B) lentiviruses (lenti) significantly increased the expression of emerin or lamin A/C in common carotid arteries the hypertensive rats. (C) Immunofluorescence staining against BrdU revealed that locally injected lentiviruses of emerin or lamin A remarkably decreased VSMC proliferation in the media of common carotid arteries of hypertensive rats. For Western blot, GAPDH was used for normalization. Values are expressed as mean ± SD. **P < 0.01 vs. the negative control (NC) (n = 6).