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Effect of partial inactivation of δ-COP on amyloid plaque formation evaluated by immunohistochemistry in the piriform cortex of 2xTg AD mice. (A) Representative images show amyloid plaques in the piriform cortex (black boxes) of male mice at 9 mo (n = 6 per genotype). (B) Quantification of the number of plaques in the piriform cortex (n = 6 per genotype). (*P < 0.05, ***P < 0.001, two-tailed Student’s t test. The results are shown as means ± SEM.)
