Table S1.
Breakdown of the number of independent tag SNPs from each of the eight candidate coatomer protein complex genes
| Gene symbol | Gene name | Chr | Start | End | Gene length, bp | Total SNPs | Initial filter | Tag SNPs |
| COPA | Coatomer protein complex, subunit alpha | 1 | 160,258,377 | 160,313,354 | 54,977 | 100 | 92 | 16 |
| COPG1 | Coatomer protein complex, subunit gamma 1 | 3 | 128,968,453 | 128,996,616 | 28,163 | 43 | 43 | 4 |
| COPB2 | Coatomer protein complex, subunit beta 2 | 3 | 139,076,433 | 139,108,522 | 32,089 | 73 | 68 | 9 |
| COPB1 | Coatomer protein complex, subunit beta 1 | 11 | 14,479,049 | 14,521,441 | 42,392 | 73 | 68 | 18 |
| COPD | Coatomer protein complex, subunit delta | 11 | 118,443,102 | 118,473,748 | 30,646 | 57 | 53 | 13 |
| COPZ1 | Coatomer protein complex, subunit zeta 1 | 12 | 54,718,911 | 54,745,633 | 26,722 | 30 | 27 | 8 |
| COPZ2 | Coatomer protein complex, subunit zeta 2 | 17 | 46,103,533 | 46,115,152 | 11,619 | 110 | 104 | 18 |
| COPE | Coatomer protein complex, subunit epsilon | 19 | 19,010,323 | 19,030,199 | 19,876 | 44 | 41 | 10 |
| Totals | 530 | 496 | 96 |
Base pair positions from the UCSC February 2009 (GRCh37/hg19) genome build. The total SNPs column contains the total number of SNPs in the gene region imputed plus observed on the Affymetrix 6.0 SNP panel. The initial filter column contains the number of SNPs remaining after removal of SNPs with MAF <0.01 in probands or that deviated from Hardy–Weinberg equilibrium (P < 0.0001) or imputed SNPs with information score <0.40.