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REVEALER results for the drug sensitivity to a MEK-inhibitor example. The target is the MEK-inhibitor PD0325901 sensitivity profile in cancer cell lines and no seed feature (NULLSEED). REVEALER iterates 3 times and identifies BRAF, KRAS and NRAS mutations, all well-known oncogenes upstream of MEK, as complementary “causes” of MEK-inhibitor sensitivity.
