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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Immunol. 2016 Mar 30;196(9):3677–3685. doi: 10.4049/jimmunol.1502709

Fig. 4. Depletion of CBPs from R36A resulted in the loss of its inhibitory effect on the cOVA-specific IgG response.

Fig. 4

BALB/c mice (7 per group) were immunized i.v. with 50 μg cOVA in alum with or without 2 × 108 CFU R36A or R36Acbp-. All mice were boosted i.v. with 50 μg cOVA in alum without bacteria, on d14. Serum titers of (A) cOVA-specific, (C) PC-specific and (D) PspA-specific IgG were measured by ELISA. (B) PC and PspA expression by R36A or R36Acbp- by flow cytometry (“control”, R36A stained with FITC-anti IgG2a only [no primary anti-PspA or anti-PC Ab]). Significance * p≤0.05.